Company origin: France. Founded in 1976, SOPHYSA was the pioneer in the development of adjustable neurosurgical valves to treat hydrocephalus. Introduced in 1984, the Sophy® valve was the first adjustable valve in the World allowing non-invasive adjustment of operating pressures, to match an individual patient's changing clinical needs.Sophysa's core competency is the management of Cerebro-Spinal Fluid, allowing her to offer a platform of products for two major medical specialties, Neurosurgery and Neurotrauma.

Company origin: Germany. Since its founding in 2005, phenox has been dedicated to developing innovative, breakthrough and clinically proven technologies and solutions for the treatment of neurovascular diseases. Today, these technologies are available in various parts of the world. phenox is constantly striving to expand into new regions making the innovations accessible to more people in the whole world. Endovascular specialists use phenox's products to treat ischemic and hemorrhagic stroke.

Company origin: Belgium. Orfit Industries NV is the world leader in the development and production of medical devices that offer solutions for immobilizing or mobilizing patients in three application fields in healthcare:
- Thermoplastic splinting materials for Physical Rehabilitation.
- Patient positioning and immobilization systems in Radiation Oncology.
- Thermoplastic sheet materials for Orthotics and Prosthetics.

Company origin: Germany. BrainLAB Sales GmbH was founded in Munich in 1989. Brainlab is first and foremost a software company with applications ranging from patient positioning in radiosurgery treatments to software-guided surgical navigation to cloud-based solutions that facilitate the secure exchange of medical images.
    Over the years, the development of hardware systems became crucial to the Brainlab portfolio. Advanced hardware expands the possibilities of treatment and facilitates and effectively delivers Brainlab software innovation across numerous fields: oncology, specifically radiotherapy and radiosurgery; image-guided surgery, specifically, craniomaxillofacial (CMF), ENT, orthopedic, spine, trauma, and neurosurgery; intraoperative imaging; integrated operating room solutions as well as image sharing and enhancement.

Company origin: Germany. Haag-Streit Surgical is one of the leaders in the development of high-precision optical systems for medicine and science.
   Since 1989 Moller-Wedel became part of the international group Haag-Streit. In 2012 all sales and marketing activities (möller-Wedel) were transferred to the newly Created Haag-Streit Surgical.
   Through an intensive exchange of ideas with the doctors at the international level, there are new trends and developments Haag-Streit Surgical. Design operating microscopes and subjective refractors is based on the requirements of medical professionals and focused on them.
   The company's products are known worldwide and is used in ophthalmology and optometry, neuro and spine surgery, otolaryngology, plastic and reconstructive surgery, and dental surgery.

Company origin: USA. Arthrex - a global medical device company and leader in new product development and medical education in orthopedics. With a corporate mission of Helping Surgeons Treat Their Patients Better™, Arthrex has pioneered the field of arthroscopy and develops more than 1,000 innovative products and procedures each year.

Company origin: China. APT Medical, a leading manufacturer and supplier of EP and Vascular Intervention medical devices, is committed to advancing the interventional medical field by utilizing technologies and innovations.